项目作者: kaiThomas236

项目描述 :
a study of the evolutionary relationships between vertebrates based on protein protein interactions. super thorough write-up in the repo. please check it out! i'm incredibly proud of this project,
高级语言: Jupyter Notebook
项目地址: git://github.com/kaiThomas236/Protein-Protein-Interactions.git


Evolutionary Relationships through Protein-Protein Interactions

This project was my Senior Capstone project. I worked in Python with NetworkX and Jupyter.
The main file is the .ipynb file, if you don’t have jupyter installed to view the file you can still get a lot of information from the write-up.
This program was built to study evolutionary relationships among a handful of vertebrate species by performing missing link prediction on their proteins.
I created a bipartite network first, between proteins and the species which have that protein, then I created both possible projections of the bipartite network, and did missing link prediction on the protein-protein projection network.
I was able to make predictions about evolutionary relationships and further research those predictions to gain a level of qualitative accuracy on them.

Please read the write-up (the pdf)! It’s incredibly detailed (though it couldn’t possibly encompass everything I learned in this project) and goes over everything I did to achieve this.