项目作者: GeoRouv

项目描述 :
🧬 Zuker: An RNA secondary structure prediction algorithm
高级语言: Jupyter Notebook
项目地址: git://github.com/GeoRouv/RNA-folding.git
创建时间: 2021-04-23T11:41:43Z
项目社区:https://github.com/GeoRouv/RNA-folding

开源协议:MIT License

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RNA-folding

An RNA secondary structure prediction algorithm

This algorithm finds all optimal secondary structures of the RNA sequence AAUACUCCGUUGCAGCAU with the following simplified Zuker minimization algorithm. The following initialisation is used:

  1. j + 5 > i => V(i, j) = W(i, j) =

hairpin energy:

  1. h(i, j) = 2 * (i - j + 5)

and stem energy:

  1. s(i, j) = -4, 0, 4 for Watson-Crick bonds, GU, and all other possible pairs respectively.

Multiloops and buldges are ignored to simplify V so that it only has the first two
cases.

In the /output folder you can find the filled-in tables W - V , an optimal fold, its bonds, and the corresponding backtrack path.