Single-cell Orientation Tracing
Single cell orientation tracing (SOT) is analysis framework for single cell RNA-seq data. SOT searches co-expreesed gene groups that represent abstract biological functions. The gene groups can be used to discover cell types and reconstruct developmental trajectory.
To install development version from GitHub, use the devtools package
install.packages("devtools")devtools::install_github("JiekaiLab/SOT")
This vignette shows the analysis of reprogramming data described in Resolving Cell Fate Decisions during Somatic Cell Reprogramming by Single-Cell RNA-seq, Molecular Cell. doi: https://doi.org/10.1016/j.molcel.2019.01.042
We welcome any bug reports, enhancement requests, and other contributions. To submit a bug report or enhancement request, please put it in issues. For more substantial contributions, please fork this repo, push your changes to your fork, and submit a pull request with a good commit message. For more general discussions or troubleshooting, please email lin_lihui@gibh.ac.cn.