A mathematical model for trans effect of 3'UTR shortening in ceRNA
Current version: 0.9.2
To better understand the role of 3ʹ-UTR shortening in regulating ceRNA gene expression, we developed a mathematical model (MAT3UTR) to quantify the trans effect of 3ʹ-UTR shortening to their affected ceRNA partner. MAT3UTR predicts ceRNA expression change based on its 3ʹUS gene(s) expression and 3ʹ-UTR shortening level, miRNA-binding site(s), and miRNA expression(s)
https://groups.google.com/forum/#!forum/mat3utr-discussion
Please click on Full Documentation to download source code and test data.
Hyun Jung Park^, Ping Ji^, Soyeon Kim, Zheng Xia, Benjamin Rodriguez, Chioniso P. Masamha, Ann-Bin Shyu, Joel R. Neilson, Eric J. Wagner, Wei Li 3ʹ-UTR Shortening Represses Tumor Suppressors in trans by Disrupting ceRNA Crosstalk. Nature Genetics, 50, 783-789 (2018)