Disable One Drive in Windows 10

Run with administrator privileges

Function Force-New-Item([String]$Path)
{
    If (!(Test-Path $Path)) {
        New-Item -Force -Path $Path
    }
}
Function RemoveAcl([String]$File)
{
    If (!(Test-Path -Path "$File")) {
        Return
    }
    $Acl = Get-Acl $File
    $Acl.SetAccessRuleProtection($true, $true)
    Set-Acl -Path $File -AclObject $Acl
    $Acl = Get-Acl $File
    $Acl.Access | Where-Object { $_.IdentityReference -NotMatch "APPLICATION PACKAGE AUTHORITY" } | ForEach {
        $Acl.RemoveAccessRule($_) 
    }
    Set-Acl -Path $File -AclObject $Acl
}
Function DisableOneDrive
{
    Stop-Process -Name "OneDrive" -Force -ErrorAction SilentlyContinue
    Stop-Process -Name "OneDriveSetup" -Force -ErrorAction SilentlyContinue
    $Paths = @("$env:SYSTEMROOT\System32", "$env:SYSTEMROOT\SysWOW64")
    ForEach ($Path in $Paths) {
        $OneDriveSetup = Join-Path -Path $Path -ChildPath "OneDriveSetup.exe"
        if (Test-Path -Path "$OneDriveSetup" -PathType Leaf) {
            Start-Process "$OneDriveSetup" "/uninstall" -NoNewWindow -Wait
            Start-Sleep -s 3
            RemoveAcl "$OneDriveSetup"
        }
    }
    Stop-Process -Name "explorer" -Force -ErrorAction SilentlyContinue
    Start-Sleep -s 2
    # Remove OneDrive from File Explorer
    $OneDrive = "HKLM:SOFTWARE\Classes\CLSID\{018D5C66-4533-4307-9B53-224DE2ED1FE6}"
    Force-New-Item -Path "$OneDrive"
    Set-ItemProperty -Path "$OneDrive" -Name "System.IsPinnedToNameSpaceTree" -Type DWORD -Value 0
    $OneDrive = "HKLM:SOFTWARE\Classes\CLSID\Wow6432Node\CLSID\{018D5C66-4533-4307-9B53-224DE2ED1FE6}"
    Force-New-Item -Path "$OneDrive"
    Set-ItemProperty -Path "$OneDrive" -Name "System.IsPinnedToNameSpaceTree" -Type DWORD -Value 0
    REG LOAD HKU\Default C:\Users\Default\NTUSER.DAT
    Remove-ItemProperty -Path "Registry::HKU\Default\SOFTWARE\Microsoft\Windows\CurrentVersion\Run" -Name "OneDriveSetup"
    REG UNLOAD HKU\Default
    $Roots = @("HKLM:\SOFTWARE", "HKLM:\SOFTWARE\Wow6432Node")
    $SubRoot = "Policies\Microsoft\Windows\OneDrive"
    $NameSpaces = Join-Path -Path $Roots -ChildPath $SubRoot
    ForEach ($OneDrive in $NameSpaces) {
        Force-New-Item -Path $OneDrive
        # Prevent the usage of OneDrive for file storage
        Set-ItemProperty -Path $OneDrive -Name "DisableFileSync" -Type DWORD -Force -Value 1
        # Prevent the usage of OneDrive for file storage
        Set-ItemProperty -Path $OneDrive -Name "DisableFileSyncNGSC" -Type DWORD -Force -Value 1
        # Save documents to OneDrive by default
        Set-ItemProperty -Path $OneDrive -Name "DisableLibrariesDefaultSaveToOneDrive" -Type DWORD -Force -Value 0
    }
    Remove-Item -Path "$env:LOCALAPPDATA\Microsoft\OneDrive" -Recurse -Force -ErrorAction SilentlyContinue 
    Remove-Item -Path "$env:PROGRAMDATA\Microsoft OneDrive" -Recurse -Force -ErrorAction SilentlyContinue 
    Remove-Item -Path "$env:SYSTEMDRIVE\OneDriveTemp" -Recurse -Force -ErrorAction SilentlyContinue
    $CommonApplicationData = [Environment]::GetFolderPath("CommonApplicationData")
    $Path = Join-Path -Path "$CommonApplicationData" -ChildPath "Microsoft OneDrive"
    Remove-Item -Recurse -Force -ErrorAction SilentlyContinue -Path $Path
}
DisableOneDrive